Both PG Play and PG Practice are accessed via the PG control panel. This means you will have access to the same features.  However, PG Play machines are generated by the Vulnhub community while PG Practice machines are created by OffSec experts.

You also have a 3 hour daily limit for PG Play machine access, while PG Practice allows unlimited access to all machines. In both PG Play and Practice, you will have access to your own machine with no one else to interfere with you.